Illinois State Police arrested 22-year-old Aldo Ruiz of Wonder Lake and 36-year-old Lamarkcus Ferguson of Country Club Hills this week.
ISP said Ruiz is responsible for a shooting July 12 on the I-90 Kennedy Expressway near East River Road on the city's Northwest Side.
One person was hurt, police said.
Ruiz has been charged with attempted murder.
Ferguson was charged in a shooting that happened July 9 on the I-94 Dan Ryan Expressway near 47th Street, state police said.
Two people were hurt in that incident.
Ferguson is facing multiple charges, including attempted murder and aggravated battery with a firearm, ISP said.
No further information was immediately available.
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