X-rays on Bryant's hand came back negative. The Cubs didn't say if Bryant would miss any time, but manager Davis Ross said he would "err on the side of caution."
"Probably some swelling in there. They said he couldn't really grip the bat," Ross said. "You assume it's going to be bad when you talk about the small body parts like the finger or the hand. You're just hoping for the best when something like that happens. I think we may be OK."
Bryant initially stayed in the game after he was hit by a first-pitch 93.4 mph sinker, then went to run at first base. He was later replaced by Patrick Wisdom.
Bryant was at third base for the second time time since April 20 after also playing at the hot corner on Saturday against St. Louis. The 29-year-old has been primarily in left field this season but also has played nine games at first base.
In a 6-for-41 slide after a hot start, Bryant is batting .292 with 13 homers and 39 RBIs.
The Associated Press contributed to this report.
Bryant hurts hand after being hit by pitch
Kris Bryant is hit by a pitch from Taijuan Walker right on his hand early in the first inning and would later leave the game.