"Those are the only ones I'm concerned with," Jenner said. "I can't let myself hurt them."
PHOTOS: Bruce Jenner through the years
The reality television star has ten children total: six biological children -- Burt, Cassandra, Brandon, Brody, Kendall and Kylie -- and four step-children -- Kourtney, Kim, Khloe and Rob Kardashian. Bruce has regularly appeared in the step-daughters' show, "Keeping Up with the Kardashians."
In addition to a life in the media spotlight, Jenner was a gold medalist for the U.S. track and field Olympic team in the 1970s. The star has received renewed attention amid rumors of an upcoming gender transition.
Jenner will sit down with Sawyer for an interview that ABC News calls "far-ranging" later this week.
"My whole life has been getting me ready for this," Jenner said.
Watch the 2-hour Bruce Jenner: The Interview on ABC on Friday, April 24 at 9 p.m. ET | 8 p.m. CT.
PHOTOS: Bruce Jenner lists Malibu home