JEFFERSON CITY, Missouri -- A tornado tore apart buildings in Missouri's capital city as part of an outbreak of severe weather across the state overnight that left at least three people dead and dozens injured.
The National Weather Service confirmed that the large and destructive twister moved over Jefferson City shortly before midnight on Wednesday.
"Across the state, Missouri's first responders once again responded quickly and with strong coordination as much of the state dealt with extremely dangerous conditions that left people injured, trapped in homes, and tragically led to the death of three people," Gov. Mike Parson said.
Jefferson City's damage spanned about a 3-mile area, said police Lt. David Williams. Emergency workers rescued about 20 people, he said, and hospitals reported treating 19 victims for injuries such as cuts and bruises. Jefferson City Police Department Lt. David Williams said in a press conference that there were no fataltities in the capital city of about 40,000. He also said that there were no missing persons reported.
The three deaths happened more than 150 miles away near Golden City in Missouri's southwestern corner.
Kenneth Harris, 86, and his 83-year-old wife, Opal, were found dead about 200 yards from their home, and Betty Berg, 56, was killed and her husband, Mark, seriously injured when their mobile home was destroyed, authorities said.
The storm also ripped a roof off a fertilizer plant in the area, prompting a precautionary evacuation within a 1-mile radius because of a possible chemical leak.
National Weather Service meteorologist Cory Rothstein said it's possible that tornado had a 50-mile path and could have been on the ground for 80 minutes. Teams were surveying the path Thursday and trying to determine whether one or multiple tornadoes had touched down.
The severe weather moved in from Oklahoma, where rescuers struggled to pull people from high water. This week has seen several days of twisters and torrential rains in the Southern Plains and Midwest.
Kerry Ann Demetrius locked herself in the bathroom of her Jefferson City apartment as the storm approached.
"We heard a loud bang. It sounded like stuff was being thrown around, everything was just banging together, and then it just went dead silent," she said. She emerged to find that the roof had been blown off her apartment building.
Austin Thomson, 25, was in the laundry room of his complex of two-story apartment buildings in Jefferson City when he saw sheets of rain coming down and a flagpole bend and slam to the ground in the wind. The windows broke, and he dove behind the washers and dryers.
After the storm had passed, he went outside to see the damage: "There's basically one building that's basically one story now."
At the Cole County Sheriff's office in Jefferson City, insulation, shingles and metal pieces lay on the ground outside the front doors.
Jefferson City school district offices were closed because many of its buildings were without power and sustained damage overnight. Also, the state high school track championships scheduled this weekend in the city were postponed, with the Missouri State High School Activities Association issuing a release that warned, "Do not travel to Jefferson City."
The weather service had received 22 reports of tornadoes by late Wednesday, though some may have been duplicate sightings of the same twister.
A tornado also skipped through the town of Eldon, population 4,900, about 30 miles outside Jefferson City, where it damaged the business district and "tore up several neighborhoods," Miller County Emergency Management Director Mike Rayhart said.
He said several people were injured seriously enough to be sent to the hospital, but he did not have specifics.
A twister also caused damage and several injuries in the town of Carl Junction, not far from Joplin, on the eighth anniversary of the catastrophic tornado that killed 161 people in that city.
The severe weather was expected to push eastward Thursday, with forecasters saying parts of the Ohio Valley and the mid-Atlantic - including Baltimore and Pittsburgh - could see tornadoes, large hail and strong winds.
Storms and torrential rains have ravaged the Midwest, from Texas through Oklahoma, Kansas, Nebraska, Iowa, Missouri and Illinois, in the past few days.
Two barges broke loose and floated down the swollen Arkansas River in Oklahoma, spreading alarm downstream as they threatened to hit a dam. On Facebook, Webbers Falls, Oklahoma, warned the town's 600 residents: "If the dam breaks, it will be catastrophic!! Leave now!!"
Authorities located the barges Thursday morning, still lashed together and stuck on rocks in the swollen river. Still, the Interstate 40 bridge and another span were closed as a precaution.
Missouri's three tornado fatalities bring to seven the number of deaths from storms this week.
ABC News contributed to this report.