Monday, health officials announced 583 new COVD-19 cases with 19 additional deaths, bringing the state's total to 20,507 positive coronavirus cases with 1,151 deaths.
RELATED: Latest updates on Indiana's coronavirus cases, deaths and response
The majority of the state moves to Phase Two of Governor Eric Holcomb's five-stage reopening plan.
Phase Two includes: Lifting travel restrictions, allowing social gatherings of up to 25 people following CDC social distancing guidelines, the opening of non-essential manufacturing and industrial operations and retail businesses, including shopping malls may open at 50-percent capacity.
RELATED: Indiana Governor Eric Holcomb releases plan to open state, ease coronavirus restrictions
Chesterton resident Dennis DeKoker said it's a positive step.
"This town has been doing pretty much what they have been asked to do by the governor, so if they feel it's safe to do it with the set guidelines, I'm all for it," DeKoker said.
But there is trepidation from others. In Chesterton, shoppers were few and far between, and shopkeepers are opening slowly.
"What my fear would be is that a whole bunch of people come in and I won't be able to regulate it, because my mom is older and my aunt is older and they both work for me," said Machelle Wagner, owner of Chelle's Boutique and Garage.
"I think that at some point they have to try it," northwest Indiana resident Dan Johnston said. "I can tell you that personally I'm gonna be watching the numbers very closely."
The Valparaiso Chamber of Commerce took a survey of its members over the phased opening and said the majority were in favor of the governor's plan, as well as the health guidelines to keep employees and customers safe.
"It's a tough issue and you have folks on all parts of the spectrum from 'this is too soon' to 'this isn't enough' and I think the governor struck a nice balance," said Valparaiso Mayor Matt Murphy.
"We have a lot of small businesses and the small businesses are really at a difficulty because of cash flow," Valparaiso Chamber of Commerce President Rex Richards said. "They need to have people come in so those businesses are going to be wanting to open as soon as possible."
Not every county s eligible to open Monday, Lake County among then. Indiana officials say testing protocol there is not yet at a point where they can offer tests to any resident, and that's where they need to be before reopening can begin.
The Indiana Health Department is set to open a new drive-through testing site in Hammond.
"It's very significant," said Michael Repay, president of the Lake County Board of Commissioners. "I think testing is the answer."
The county partnered with Methodist Hospitals and Opus Inspection to set up Hammond's first testing location.
"In order to get on top of this order to get to the other side, we need to test more people," Repay said.
County officials said residents must bring their state ID to show you are a Lake County residents, and must show symptoms of the virus to get tested. Hammond's site off Gostlin and Magnolia will be able to test about 100 people per day and will be open for at least five days.
"If we have an opportunity where we get, you know, a better handle on supplies, et cetera, we're going to, you know, expand that," Repay said.
In Michigan City proximity to Chicago has people reticent about opening too fast.
"I think the feeling in the community is one of uncertainty, people do not know whether it is safe to go back to work or go back to their lives," said Kenneth Allen, civil rights lawyer and community leader.
That's why Michigan City's outlet mall and surrounding closed retailers will not be opening yet. The decision was made by the mayor, the first Republican to preside there for years.
"We are not out of this pandemic, and just because people say we are on the downside of this curve doesn't mean we can act like there's nothing out there anymore," said Michigan City Mayor Duane Parry.
Likewise, leaders in Porter County are urging residents to take precautions to stay safe.
"The virus is still out there," said Portage Mayor Sue Lynch. "We need to continue to practice with caution and keep our distance.
Lake, Marion and Cass counties will move to Phase Two at a later date.
Here's how reopening look in Indiana:
Stage 3 begins May 24, with playgrounds, gyms and movie theaters allowed to reopen.
Stage 4 is June 14, with bars and nightclubs allowed to reopen
Stage 5 is July 4; fairs and festivals will be allowed, and retail and restaurants can operate at full capacity.