Thursday, 20-year-old Sergio Garcia was killed in the 1300-block of West 48th Street, and 18-year-old Ricardo Alcantar was killed in the 4800-block of South Hamlin.
Early Friday morning, 18-year-old Zachary Barrios was shot to death in the 10600-block of South Champlain.
Those injured include a 15-year-old boy who is in critical condition after he was shot Thursday night in the 1600-block of West 60th Street.