The Chicago company, which has been family owned and operated since 1947, did not say how Perrino died.
"Joe was both a leader and the family patriarch, who over the years, inspired and touched numerous lives. He will be greatly missed," the company said in a statement.
Home Run Inn is known for its thin-crust pizza and has 10 pizzerias throughout the Chicago area. It is also the top-selling frozen pizza brand in the Chicago area, and is sold in 40 states.