The fire broke out around 11:15 p.m. Thursday in the 2500-block of West 25th Street. Smoke and flames could be seen for miles.
The blaze burned through three buildings at least half a dozen semi-trailers and thousands of pallets used to support various goods for transport.
Firefighters had a hard time pumping water from the neighborhood to the scene and one hose started to collapse as they worked to put out the flames. They had the fire under control by around 1 a.m. Friday.
Several units were still on the scene around 5 a.m., dousing hot spots with water from the top of an extended ladder.
No injuries were reported. The cause of the fire is under investigation.