The testing site at Loretto Hospital is open to the public along with healthcare workers and first responders.
The site will provide rapid nasopharyngeal (NP) or nose swab testing with patient results available in about 72 hours.
Coronavirus: Latest news and updates on Illinois COVID-19 cases, Chicago area impact
The test is free and the site is open Monday through Friday from 9 a.m. to 4 p.m.
Both drive-up and walk-in testing options are available.
RELATED: Coronavirus testing: Where to get tested for COVID-19 in Illinois, Chicago area
The hospital received 500 test kits from the state to start and will order more kits as needed.
Local community organizers have been protesting for more testing sites on the south and west sides.
They believe increased testing in underserved communities will help address what they argue are racial disparities in healthcare.
WATCH: Black community leaders call for more health care at South and West side hospitals
645 S Central Ave
Chicago, IL 60644