Police said officers started chasing Jamayel Tillman, 31, in the 9100-block of South Martin Luther King Drive after they spotted him making a traffic violation Thursday night.
The officers stopped that chase just before Tillman ran a red light at East 75th Street and South Jeffery Avenue and crashed into another vehicle around 10:15 p.m., police said.
Ten people were taken to area hospitals. Six were listed in fair-to-serious condition. Four were listed in good condition. Four other people refused medical attention.
Tillman, of the 7900-block of South Peoria Street, was arrested and charged with three felony counts of fleeing police, one misdemeanor count of driving with a suspended license and one misdemeanor count of driving without insurance. He is due in bond court Friday.
The Sun-Times Media Wire contributed to this report.