Edwards is accused of driving the get-away car, during the gang execution of Lee last November.
A judge in court on Wednesday says the crime, "shocked the city to the core and shocked the nation" because the victim was so young.
Anthony Guglielmi, Chicago Police Department Communications Director, tweeted about the murder charges Wednesday morning.
Murder charges filed against Kevin Edwards in the targeted execution of Tyshawn Lee. Case is now closed with the arrest of 3 offenders.— Anthony Guglielmi (@AJGuglielmi) May 18, 2016
Edwards, 23, was taken into custody May 14 in downstate Danville.
Two other men are charged in Tyshawn's murder. Police said in November 2015, Corey Morgan lured the child into the alley where Dwright Boone-Doty shot the boy several times at close range.
Investigators believe the murder was part of a gang retaliation against Tyshawn's father, Pierre Stokes.
Thanks to the CPD team who worked tirelessly to seek justice for Tyshawn. Their perseverance speaks volumes abt how much they cared abt him— Anthony Guglielmi (@AJGuglielmi) May 18, 2016
Investigators say the case is now closed.