Bickell, 31, was a member of the three Stanley Cup champion teams with the Blackhawks.
The 31-year-old Ontario native shared in November of 2016 that he has multiple sclerosis. He was with the Carolina Hurricanes at the time.
"I'm honored to be retiring a Chicago Blackhawk-a team that has given me and my family so many great memories." https://t.co/dw3xgDMAZu— Chicago Blackhawks (@NHLBlackhawks) October 4, 2017
Bickell was originally selected in the second round of the 2004 NHL Draft by the Blackhawks.
He and his wife, Amanda Bickell, also run the Bryan & Amanda Bickell Foundation which seeks to create awareness and compassion for "pit bull" type dogs and work with them to help abused children.