The victims include an 11-year-old girl who is in critical condition, a 12-year-old girl, along with 12 and 15-year-old boys and a 35-year-old man all listed in stable condition. The crash happened on the South Side near 63rd and St. Lawrence.
Police say the suspects were driving a stolen car when they hit the victims then crashed into another car.
Surveillance video captured the accident.
The crashed car is a Chrysler 300 with Indiana license plates.
People with information about the accident are urged to contact Chicago police.