His death came Friday but was just announced Sunday.
Wade had a 55-year career in broadcasting, including 27 years in Chicago at WLS.
During that career, his work ranged from comedy to rock and roll DJ.
At WLS Wade and his wife Roma began hosting their long running morning talk show in 1989.
Sunday night Roma issued a statement saying: "We had a lifetime of blessings together and one of the very best was sharing our thoughts, our family, our joys and sorrows with you, our radio family. You meant the world to us."
Don Wade was 72.
"As a city, we are saddened to hear of the passing of Don Wade. For nearly three decades, Don entertained and enlightened his listeners and the lifetime of contributions he made to our city will be truly missed. Don's zeal for his job was matched only by his love for his wife Roma and though his voice has fallen silent, his influence will echo on in Chicago for years to come," said Chicago Mayor Rahm Emanuel.
For more information: Don Wade WLS-AM memorial page