Police said the first attack occurred about 10:30 p.m., when a group of three girls approached a 24-year-old woman on foot and sprayed her as she stood outside in the 1100 block of South State Street. The woman was treated and released from Mercy Hospital, police said.
Shortly after, a 26-year-old woman was also sprayed in the 1300 block of South State Street. The woman's injuries were treated on the scene, police said.
Three female juveniles have been charged with battery and simple assault, both misdemeanors, police said. They are scheduled to appear in juvenile court.
Police could not offer a motive for the attacks.
Sun-Times Media contributed to this article.