It happened just 12 a.m. Monday at East 141st Street and Indiana in Dolton.
The car smashed right through the wall and burned part of the home.
The homeowner said he thought it was something much worse, at first.
"All of a sudden, we heard a loud boom, and she jumped up, got on the floor like somebody was shooting. I looked out the back, and there was car in the basement, knocked out half the wall in the basement," the unidentified man said.
The driver of the car went to the hospital with a leg injury.
No one inside the home was hurt.