In a study of more than 500 men the urine test was 85 percent successful in classifying men as cancer free.
The current screening method is the PSA blood test. That is often inaccurate.
Researchers say adding the gene test may not only better predict which men have prostate cancer, but which tumors are more aggressive.
Results of the new study were presented at the Genitourinary Cancers Symposium taking place in Orlando, Florida.