Enterprise Rent-A-Car says it will stop offering car rentals through Orbitz and its sister site, Cheap Tickets.com as of April 1.
Enterprise is the world's largest car-rental company. It also operates Alamo and National Car rental brands.
Enterprise says it's ending its relationship with Chicago-based Orbitz following its decision to remove Alamo and National Car rental listings and raise its commissions.
Orbitz says it was unable to reach mutually agreeable terms with Enterprise.