It happened about 1:30 Tuesday afternoon on a rural stretch of track in Copiah County, south of Jackson.
The City of New Orleans train left Chicago Monday night. It was due into Louisiana Tuesday afternoon.
About 100 passengers were moved to a shelter at a school near the crash scene. They were scheduled to complete their trip by bus.Three of those taken to hospitals were Amtrak employees who suffered non-life-threatening injuries, Amtrak spokesman Marc Magliari said. He did not know the status of the others hurt, or whether they were train passengers, truck passengers or both. A fire broke out after the collision, authorities said, damaging the engine. The train's final car, which was empty, left the track. Matt Morning of St. Louis, who was returning to school at the University of New Orleans, said he and another student were eating in the dining car when the accident occurred. "We were just sitting when all of the sudden we felt this incredible jolt," Morning said. He said it felt like the train was going to jump the tracks. Morning said people came into the dining car and told everyone to stay put. "They later came back and directed us to the exits. We're just kind of stranded," Morning said. The northbound City of New Orleans was held at the station just as it was set to depart Tuesday afternoon, Magliari said. Canadian National Railway owns the tracks.
The Associated Press contributed to this report.