Drivers will now pay $8.80 to travel the entire length of the 157-mile tollway by car. The price will vary for different types of vehicles.
One group that won't be paying more are cars with the I-Pass or I-Zoom transponders.
The Indiana Toll Road was privatized in 2006. Under terms of the lease, there will be a rate increase on July 1 for the next 71 years.