The extra security included wanding, searching people before entering the gymnasium and a strong police presence.
The last time they met there was a brawl on the court and following the game, there was a deadly shooting in the parking lot.
The head coaches of both teams were suspended for four days for the on-court fight.
The two schools are powerhouse teams and fierce rivals. The game was being called "The Battle of Vincennes" after the street both schools are located on.
CPS issued a statement saying that they believe "will be played in a sportsmanlike atmosphere" and they have worked with Chicago State University and Chicago police on a security plan for the game.