Scientists say they have found the first inherited link to common types of migraines.
The tiny variant can be found on Chromosome 8 between two genes. It's thought to help regulate a chemical called glutamate.
This chemical may accumulate in junctions between brain cells and scientists think this unleashes the migraine. If so, drug engineers say it gives them a tempting new target for treatment.
There is more on the research in the journal Nature Genetics.