State police from Illinois, Wisconsin, Michigan and Indiana will concentrate on the Interstate 94 corridor.
They'll be concentrating on speeding, texting, alcohol use, reckless driving and failure to wear seat belts. They say they'll have zero tolerance for violations.
One Illinois trooper was severely injured by a distracted driver in 2010 on I-94.
"I was standing outside my vehicle and another unit that was, she was distracted by her cell phone, wasn't paying attention and she struck me and I sustained injuries to my right leg, left leg and my pelvis," said Illinois State Trooper Starlena Wilson.
More than half of fatal accidents involve alcohol, speeding or distracted driving, and one-third of people involved are not wearing seat belts.