A Chicago-based Amtrak spokesperson initially wrote in a statement that the train was headed to Chicago, but that statement was clarified later Sunday.
According to the statement, the derailment happened at approximately 10:10 a.m. and that there were fewer than a dozen injuries.
"There are no reports of serious or life-threatening injuries," the statement read.
Niles, Mich. police said the train derailed at Progressive and Terminal, approximately an hour and a half away from Chicago.
According to the spokesperson, passengers who did not need medical attention were put on another train from Niles to Chicago.
Authorities say the cause of the incident is under investigation.