It happened early Sunday morning in the Albany Park neighborhood.
Officers say the man came in through the victim's window, in the 4800 block of North Ridgeway and sexually abused her when she was sleeping in her bed.
"I want protection because I got a lot of kids, and my niece, and I have my nephew, I have a lot of people here, and they're babies. And I need protection from the police," said resident Patricia Ovale.
Police do not have a good description of the suspect.
They're urging all residents in the area to lock all doors and windows and report any suspicious activity.