Relatives waited nervously outside the hospital Monday night as doctors treated the gunshot wound.
Khalise Weatherspoon just turned 4 years old over the weekend.
Police combed the scene near 71st and Rockwell looking for evidence, hoping it will lead to the suspects who opened fire.
Some witnesses say one or possibly two men emerged from the alley and started shooting.
One bullet struck little Weatherspoon in the abdomen.
Relatives rushed Weatherspoon from the scene to Holy Cross Hospital, but doctors quickly decided she needed to be at a trauma center so they brought her to Mount Sinai.
Relatives say she seems to be doing better, but they want the violence to stop.