The Reynosos were fatally shot in their apartment at the Baldwin Green complex in the 1900-block of Green Lane North. They were found just after midnight on Wednesday, and pronounced dead at a local hospital.
Luis was shot multiple tines, according to an autopsy. Segundo was shot once in the head.
Police said Luis was known to have gang ties, and they had been called out to the address before.
Police have not released details in the shooting.